Loved By Our Customers

KEY INGREDIENTS

Skin Rejuvenator - to stimulate collagen production, promotes cell regeneration, and reduce fine lines for a firmer, brighter, and more youthful appearance.

Hydration Hero - replenishes and locks in moisture, leaving skin soft, supple, and deeply hydrated.

Skin Smoother - helps soothe and support the skin’s natural protective barrier.

Skin Brightener & Barrier Booster - visibly improves skin clarity, enhances texture, and supports a stronger skin barrier for a more even-looking complexion.

Before and after

YURSLF model pdrn Before
After

RAMITA, 60

Image shows results after 2.5 months of daily use. Improvement in fine lines, hydration, undereyes & skin brightness

SKIN IMPROVEMENT TIMELINE

Anti-aging science

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YURSLF cell proliferation results cell proliferation results
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YURSLF product information YURSLF skincare in bright light for sensitive skin
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TOXIN FREE SKINCARE

Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, sulfates SLS & SLES, triclocarban, triclosan, and contains less than one percent synthetic fragrance. It is also comes in recyclable packaging.

REVIEWS

*For cosmetic use only. Not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.

Dr. Jennifer Tsai, OD

I’m naturally skeptical of most at-home treatments but YURSLF genuinely surprised me. Its high concentration of 50,000 ppm salmon-derived PDRN shows its ability to support collagen and elastin production by activating fibroblasts. It also engages A2A receptors, which play a key role in hydration and barrier repair. While I always encourage in-office treatments for more targeted results, this has become one of the few at-home options I like recommending especially for those looking to extend their results between visits or explore a needle-free alternative to support skin longevity. 

FREQUENTLY ASKED QUESTIONS

Salmon DNA is a topical ingredient that does not enter the bloodstream and is considered suitable for use during pregnancy.

Salmon DNA (Polydeoxyribonucleotide) is a naturally derived DNA compound extracted from salmon sperm cells. It’s known for helping skin regenerate, reduce inflammation, and rebuild its structure making it ideal for anti-aging and healing.

It binds to A2A purinergic receptors, activating a repair process at the cellular level. This stimulates fibroblasts to produce more collagen and elastin, increases skin turnover, and reduces inflammatory responses.

Yes! Salmon DNA is highly compatible with human skin. It’s purified, broken down into small fragments, and rigorously tested for cosmetic safety. It’s already used in hospitals and clinics in Korea and Europe for wound and scar healing.

A serum is designed for daily use, while an ampoule is typically a more concentrated, treatment-focused formula.

Clinical testing showed visible effects starting at 2–5%, with optimal collagen-boosting results at 10%concentration. Salmon DNA is used in this range for measurable results.

While its main function is skin regeneration, Salmon DNA indirectly helps fade pigmentation and acne scars by accelerating skin turnover and improving texture. Some studies have also noted anti-melanogenic effects (i.e., it may help suppress new pigmentation).

With consistent use, expect smoother texture, better hydration, firmer skin, and a gradual softening of fine lines and wrinkles. Many users also report quicker recovery from irritation or treatments like microneedling.

Not at all. Salmon DNA and other cosmetic-grade PDRNs are purified and odorless. The final product has no scent or fish-related properties.

Rejuran is an injectable treatment used in clinics, while Salmon DNA is a topical-grade version that can be used daily at home. Both use salmon DNA, but Salmon DNA is processed into low molecular weight fragments for better absorption through the skin barrier.

They’re not better or worse just different, and actually work best together. Hyaluronic acid is a hydration powerhouse that plumps and moisturizes the skin instantly. Peptides help signal skin to maintain firmness and structure. Salmon DNA goes deeper, triggering the skin’s natural regeneration process by encouraging new cell growth and collagen synthesis. In our formula, we combine Salmon DNA with a hyaluronic acid complex so you get both immediate hydration and long-term rejuvenation.

Yes. Salmon DNA has been clinically studied since the early 2000s in Italy and Korea. A 2016 study (Int. J. Mol. Sci.) confirmed its anti-inflammatory and regenerative properties, and a 2013 study (Dermatology Research and Practice) validated its safety for dermal use.

Sodium DNA" is the INCI (cosmetic ingredient) name for water-soluble Salmon DNA. It's the form used in topical skincare and is functionally the same as cosmetic-grade Salmon DNA.

Some users notice early changes within 1–2 weeks. More visible improvements typically appear after about 4 weeks of consistent use.

Skin renews itself in roughly 4 week cycles. Supporting consecutive renewal cycles allows improvements to build instead of resetting.

Apply it to clean skin before heavier serums or moisturizers. It layers easily with most routines.

No. This product supports skin quality, texture, and fine lines. Injectables address muscle movement or volume and serve different purposes.

Yes. Like most skincare, benefits are maintained with ongoing use. Stopping use can gradually slow or reverse progress.

Yes, absolutely! Salmon DNA can be used alongside tretinoin or retinol and is often layered to help support skin repair and barrier recovery. We always recommend patch testing prior to full use, especially when combining with active ingredients, to ensure your skin responds well.