Formulated in Korea
◆
50,000 PPM PDRN
◆
Real salmon DNA
◆
Fragrance-free
◆
Sensitive-skin safe
◆
Formulated in Korea
◆
50,000 PPM PDRN
◆
Real salmon DNA
◆
Fragrance-free
◆
Sensitive-skin safe
◆
Formulated in Korea
◆
50,000 PPM PDRN
◆
Real salmon DNA
◆
Fragrance-free
◆
Sensitive-skin safe
◆
Formulated in Korea
◆
50,000 PPM PDRN
◆
Real salmon DNA
◆
Fragrance-free
◆
Sensitive-skin safe
◆
Begin Your Ritual
PDRN Ampoule
★★★★★ 4.9 / 4,200+ reviews
MADE IN KOREA
50,000 PPM
Pain free
Targets Fine lines, firmness, wrinkles, skin barrier, dark spots, dullness, and dryness.
Suited for All skin types, safe for sensitive skin.
Formulation Highly concentrated, fragrance-free ampoule.
Amount 20ml (2 × 10ml) — 1-month dose.
60ml (6 × 10ml) — 3-month dose.
Each 10ml ampoule lasts 2 weeks with daily use.
Your skin changed.
Your routine should too.
Clinically focused anti-aging care in one concentrated step. It helps your skin make its own collagen resulting in smoother, plumper, younger-looking skin with every use. Korea’s gold standard for anti-aging and glass skin.
★★★★★
4.9
from 4,200+ reviews
Free shipping · Pain-free · 21,000+ Members
As seen in
ALLURE
VOGUE
COSMOPOLITAN
As seen in
ALLURE
VOGUE
COSMOPOLITAN
The Results
Clinical results,
at-home.
YURSLF supports natural skin renewal and collagen production, helping skin look plumper, smoother and brighter over time without injections.
Independent 12-week study
Dermatologist-graded
No injectables
92%
individuals report smoother, brighter looking-skin after one use
86%
said their skin looked smoother, plumper, and more radiant after consistent use
35%
increase in collagen production during clinical testing
The Results
Clinical results,
at-home.
YURSLF supports natural skin renewal and collagen production, helping skin look plumper, smoother and brighter over time without injections.
Independent 12-week study
BACKED BY CLINICAL DATA
No injectables
Unretouched participant photos · individual results vary
The Results
Clinical results,
at-home.
YURSLF supports natural skin renewal and collagen production, helping skin look plumper, smoother and brighter over time without injections.
Independent 12-week study
Dermatologist-graded
No injectables
Unretouched participant photos · individual results vary
The Results
Clinical results,
at-home.
YURSLF supports natural skin renewal and collagen production, helping skin look plumper, smoother and brighter over time without injections.
Independent 12-week study
BACKED BY CLINICAL DATA
No injectables
92%
individuals report smoother, brighter looking-skin after one use
86%
said their skin looked smoother, plumper, and more radiant after consistent use
35%
increase in collagen production during clinical testing
Why It Works
One ampoule.
Everything your skin is asking for.
Pain-Free
One Easy Step
Made in Korea
Because Salmon DNA closely mirrors Human DNA, your skin recognizes it and responds by signalling your skin to start repairing itself.
1
Works where creams stop
PDRN signals your fibroblasts to produce collagen and elastin. Rebuilding structure, not just coating the surface.
2
Clinic-grade, at home
50,000 PPM — the highest topical PDRN available, the same active behind in-clinic salmon-DNA facials.
3
A glow that compounds
This isn't a one-night glow. With daily use, skin acts and appears younger. The results build the longer you stay with it.
Real Salmon PDRN
Pain-Free · Fragrance-Free
Made in Korea
What's Inside
Highly concentrated, intentional formula. Every ingredient earns its place — nothing for marketing, nothing for filler.
SALMON DNA 50,000 PPM
Skin Rejuvenator - to stimulate collagen production, promotes cell regeneration, and reduce fine lines for a firmer, brighter, and more youthful appearance.
HYALURONIC ACID COMPLEX
Hydration Hero - Several molecular weights of HA hydrate at different depths. Replenishes and locks in moisture, leaving skin soft, supple, and deeply hydrated.
NIACINAMIDE
Skin Brightener & Barrier Booster - visibly improves skin clarity, enhances texture, and supports a stronger skin barrier for a more even-looking complexion.
MADECASSOSIDE
Skin Smoother - A purified active from Centella Asiatica. Helps soothe and support the skin’s natural protective barrier.
Trusted by Beauty Insiders
They don't just
recommend it. They use it.
The Ritual
How to use it
morning or night.
Step 01
Cleanse
Start with freshly washed, towel-dried skin.
Step 02
Apply
Press 1-2 drops per target area gently into your face and neck.
Step 03
Layer
Follow with your serums, moisturizer, SPF, or makeup.
Step 04
Repeat
Use daily. Skin acts and appears younger the longer you stay consistent.
The Difference
Better skin.
Less spend.
YURSLF
The old way
✓
Rebuilds skin at the cellular level
✕
Only hydrates the surface
✓
Real salmon-DNA PDRN at 50,000 PPM
✕
Plant substitutes at 5,000–10,000 PPM
✓
One gentle daily step, sensitive-safe
✕
A stack of serums & clinic visits
$95
$639+
One daily ampoule replaces the serums, essences, and in-clinic aesthetics — saving $470+
Loved by our customers
Questions
Everything you
might be wondering.
Is Salmon DNA Pregnancy Safe?
Salmon DNA is a topical ingredient that does not enter the bloodstream and is considered suitable for use during pregnancy.
Does it hurt or sting like retinol?
Not at all. Unlike retinol or other strong actives, the ampoule is completely pain-free — no stinging, peeling, or purging. It actually supports your barrier, which is why it's safe for sensitive skin.
Can I use this with tretinoin or retinol?
Yes, absolutely! Salmon DNA can be used alongside tretinoin or retinol and is often layered to help support skin repair and barrier recovery. We always recommend patch testing prior to full use, especially when combining with active ingredients, to ensure your skin responds well.
How does Salmon DNA work in the skin?
It binds to A2A purinergic receptors, activating a repair process at the cellular level. This stimulates fibroblasts to produce more collagen and elastin, increases skin turnover, and reduces inflammatory responses.
Will it smell like fish?
Not at all. Salmon DNA and other cosmetic-grade PDRNs are purified and odorless. The final product has no scent or fish-related properties.
What exactly is PDRN?
PDRN (polydeoxyribonucleotide) is a regenerative ingredient used in clinics to stimulate skin repair. It signals your own cells to renew — building collagen, accelerating turnover, and improving hydration. It's the most clinically studied ingredient in regenerative skincare.
Is it really made with salmon DNA?
Yes. We use real salmon-derived PDRN rather than synthetics or plant substitutes, because salmon DNA is the most bio-compatible with human skin, which is what makes it work so well.
Can I use it with my other actives and makeup?
Yes. It has a silky, non-sticky finish that layers beautifully under makeup and pairs with every other step in your routine — serums, moisturizer, SPF. No conflicts, no pilling.
How soon will I see results?
Many members notice glow and hydration within the first couple of weeks. Firmness and fine-line improvements build over 8+ weeks — this is renewal that compounds, so consistency matters. That's why the 3-month plan is most popular.
What’s the difference between this and injectable PDRN like Rejuran?
Rejuran is an injectable treatment used in clinics, while Salmon DNA is a topical-grade version that can be used daily at home. Both use salmon DNA, but Salmon DNA is processed into low molecular weight fragments for better absorption through the skin barrier.
Are there any clinical studies to back this up?
Yes. Salmon DNA has been clinically studied since the early 2000s in Italy and Korea. A 2016 study (Int. J. Mol. Sci.) confirmed its anti-inflammatory and regenerative properties, and a 2013 study (Dermatology Research and Practice) validated its safety for dermal use.
How do I use Salmon DNA with my existing skincare routine?
Apply it to clean skin before heavier serums or moisturizers. It layers easily with most routines.