Formulated in Korea
◆
The gentle alternative to retinol
◆
No burning, No peeling
◆
Fragrance-free
◆
Sensitive-skin safe
◆
Formulated in Korea
◆
No burning, No peeling
◆
The gentle alternative to retinol
◆
Fragrance-free
◆
Sensitive-skin safe
◆
Formulated in Korea
◆
The gentle alternative to retinol
◆
No burning, No peeling
◆
Fragrance-free
◆
Sensitive-skin safe
◆
Formulated in Korea
◆
No burning, No peeling
◆
The gentle alternative to retinol
◆
Fragrance-free
◆
Sensitive-skin safe
◆
Renewal without the pain
5 reasons why everyone
stopped using retinol
YURSLF delivers everything you wanted from retinol, firmer, smoother, more even skin by repairing your skin instead of irritating it. All the renewal. None of the burn.
See the 5 reasons ↓
21,000+
Members
4.9 ★
4,200+ reviews
Zero
Burn · peel · purge
As seen in
ALLURE
VOGUE
Byrdie
ELLE
Cosmopolitan
01
Because "beauty is pain" was a lie we all believed
Somewhere along the way you were sold the idea that flaking, stinging and weeks of redness are proof a product is "working." They aren't. That's your skin's barrier breaking down with every use.
"For years we accepted that effective meant irritating. PDRN changed that. I now reach for it before retinoids. The renewal is real, and the barrier stays intact."
Dr. Emilija Minova
Dermatologist
Highest topical dose
50,000 PPM PDRN
02
Because skin damage was never proof of progress
Retinol works through controlled injury by accelerating shedding and provoking your skin until it renews, and the redness and peeling are the price of admission. YURSLF works the opposite way: it signals your cells to rebuild collagen, speed turnover and reinforce the barrier from within.
YURSLF
✓
Renews by repairing & rebuilding skin
✓
No purge, no peeling, no downtime
✓
Strengthens & calms the barrier
✓
Safe for sensitive skin & pregnancy-conscious routines
Retinol / tretinoin
✕
Renews by irritating & shedding skin
✕
Weeks of redness, flaking & the "purge"
✕
Thins the barrier · sun-sensitive
✕
Off-limits when sensitive, pregnant or nursing
Everything retinol does for your skin; firmer, smoother, more even without the weeks of recovery you've learned to dread.
03
Because the barrier retinol strips is the one keeping you young
A strong skin barrier is what holds in moisture, keeps out irritation, and keeps skin looking plump and resilient. Years of retinol and acids quietly wear it down. PDRN does the opposite: it reinforces the barrier while it renews, so skin gets calmer, stronger and firmer at the same time.
★★★★★
"My skin is looking younger and no more irritation"
The instant payoff
96%
felt zero irritation
0%
Redness or peeling
92%
More hydrated skin
94%
Firmer, smoother by 8 weeks
*Based on a consumer use study. Individual results vary.
Miranda Wilson
✓
Nurse Practitioner
04
Because real salmon DNA does what retinol can't
PDRN aka Salmon DNA is the most bio-compatible with human skin. It signals your cells to regenerate collagen, accelerate turnover and reinforce the barrier. The same deep, structural renewal retinol mimics, but without the damage.
05
Because gentle is the only routine that actually works
The real secret to results? Skincare you don’t have to quit. Retinol routines get skipped because your skin can’t always take it. YURSLF is designed for daily renewal without pain, burning, peeling, or irritation, so results can compound over time.
★★★★★
12-week results
Trusted by Beauty Insiders
They don't just
recommend it. They use it.
The Results
Clinical results,
at-home.
YURSLF supports natural skin renewal and collagen production, helping skin look plumper, smoother and brighter over time without injections.
Independent 12-week study
Dermatologist-graded
No injectables
Unretouched participant photos · individual results vary
The Results
Clinical results,
at-home.
YURSLF supports natural skin renewal and collagen production, helping skin look plumper, smoother and brighter over time without any pain.
Independent 12-week study
BACKED BY CLINICAL DATA
No Pain
92%
individuals report smoother, brighter looking-skin after one use
86%
said their skin looked smoother, plumper, and more radiant after consistent use
35%
increase in collagen production during clinical testing
The Results
Clinical results,
at-home.
YURSLF supports natural skin renewal and collagen production, helping skin look plumper, smoother and brighter over time without injections.
Independent 12-week study
Dermatologist-graded
No injectables
92%
individuals report smoother, brighter looking-skin after one use
86%
said their skin looked smoother, plumper, and more radiant after consistent use
35%
increase in collagen production during clinical testing
The Results
Clinical results,
at-home.
YURSLF supports natural skin renewal and collagen production, helping skin look plumper, smoother and brighter over time without any pain.
Independent 12-week study
BACKED BY CLINICAL DATA
No pain
Unretouched participant photos · individual results vary
The Ritual
How to use it
morning or night.
Step 01
Cleanse
Start with freshly washed, towel-dried skin.
Step 02
Apply
Press 1-2 drops per target area gently into your face and neck.
Step 03
Layer
Follow with your serums, moisturizer, SPF, or makeup.
Step 04
Repeat
Use daily. Skin acts and appears younger the longer you stay consistent.
What's Inside
Highly concentrated, intentional formula. Every ingredient earns its place — nothing for marketing, nothing for filler.
SALMON DNA 50,000 PPM
Skin Rejuvenator - to stimulate collagen production, promotes cell regeneration, and reduce fine lines for a firmer, brighter, and more youthful appearance.
HYALURONIC ACID COMPLEX
Hydration Hero - Several molecular weights of HA hydrate at different depths. Replenishes and locks in moisture, leaving skin soft, supple, and deeply hydrated.
NIACINAMIDE
Skin Brightener & Barrier Booster - visibly improves skin clarity, enhances texture, and supports a stronger skin barrier for a more even-looking complexion.
MADECASSOSIDE
Skin Smoother - A purified active from Centella Asiatica. Helps soothe and support the skin’s natural protective barrier.
Loved by our Customers
Begin Your Ritual
PDRN Ampoule
★★★★★ 4.9 / 4,200+ reviews
MADE IN KOREA
50,000 PPM
Pain free
Targets Fine lines, firmness, wrinkles, skin barrier, dark spots, dullness, and dryness.
Suited for All skin types, safe for sensitive skin.
Formulation Highly concentrated, fragrance-free ampoule.
Amount 20ml (2 × 10ml) — 1-month supply
60ml (6 × 10ml) — 3-month supply.
Each 10ml ampoule lasts 2 weeks with daily use.
Questions
Everything you
might be wondering.
Why should I subscribe?
Subscribing is the best way to get the full benefits while saving significantly.
This product is designed for daily, consistent use, not occasional application. With regular use, the results build over time: supporting collagen production, strengthening the skin barrier, and helping skin look brighter, healthier, and more resilient.
Think of it like a daily supplement for your skin. One time use can’t deliver lasting results.
Is Salmon DNA Pregnancy Safe?
Salmon DNA is a topical ingredient that does not enter the bloodstream and is considered suitable for use during pregnancy.
Does it hurt or sting like retinol?
Not at all. Unlike retinol or other strong actives, the ampoule is completely pain-free — no stinging, peeling, or purging. It actually supports your barrier, which is why it's safe for sensitive skin.
Can I use this with tretinoin or retinol?
Yes, absolutely! Salmon DNA can be used alongside tretinoin or retinol and is often layered to help support skin repair and barrier recovery. We always recommend patch testing prior to full use, especially when combining with active ingredients, to ensure your skin responds well.
How does Salmon DNA work in the skin?
It binds to A2A purinergic receptors, activating a repair process at the cellular level. This stimulates fibroblasts to produce more collagen and elastin, increases skin turnover, and reduces inflammatory responses.
Will it smell like fish?
Not at all. Salmon DNA and other cosmetic-grade PDRNs are purified and odorless. The final product has no scent or fish-related properties.
What exactly is PDRN?
PDRN (polydeoxyribonucleotide) is a regenerative ingredient used in clinics to stimulate skin repair. It signals your own cells to renew — building collagen, accelerating turnover, and improving hydration. It's the most clinically studied ingredient in regenerative skincare.
Is it really made with salmon DNA?
Yes. We use real salmon-derived PDRN rather than synthetics or plant substitutes, because salmon DNA is the most bio-compatible with human skin, which is what makes it work so well.
Can I use it with my other actives and makeup?
Yes. It has a silky, non-sticky finish that layers beautifully under makeup and pairs with every other step in your routine — serums, moisturizer, SPF. No conflicts, no pilling.
How soon will I see results?
Many members notice glow and hydration within the first couple of weeks. Firmness and fine-line improvements build over 8+ weeks — this is renewal that compounds, so consistency matters. That's why the 3-month plan is most popular.
What’s the difference between this and injectable PDRN like Rejuran?
Rejuran is an injectable treatment used in clinics, while Salmon DNA is a topical-grade version that can be used daily at home. Both use salmon DNA, but Salmon DNA is processed into low molecular weight fragments for better absorption through the skin barrier.
Are there any clinical studies to back this up?
Yes. Salmon DNA has been clinically studied since the early 2000s in Italy and Korea. A 2016 study (Int. J. Mol. Sci.) confirmed its anti-inflammatory and regenerative properties, and a 2013 study (Dermatology Research and Practice) validated its safety for dermal use.
How do I use Salmon DNA with my existing skincare routine?
Apply it to clean skin before heavier serums or moisturizers. It layers easily with most routines.
30-Day Promise