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17
★★★★★
4.9
4,200+ reviews
Clinic-grade salmon DNA in one daily step. It helps skin make more of its own collagen, so it looks smoother, plumper and brighter with every use.
3-Month Dose
SAVE $174
60ml · 6 × 10ml ampoules
$58/mo · billed every 3 months
$174
$348
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Details
Targets Fine lines, firmness, wrinkles, skin barrier, dark spots, dullness and dryness.
Suited for All skin types, including sensitive.
Formulation Highly concentrated, fragrance-free ampoule.
Amount 20ml (2 × 10ml) for one month, or 60ml (6 × 10ml) for three. Each 10ml ampoule lasts two weeks with daily use.
How to use
Use daily after cleansing, and after toner if you use one. Apply to face and neck, then follow with your usual skincare.
Shipping
Orders process in 1–2 business days. USA delivery takes 2–6 business days and GCC takes 1–3. Everything ships locally, so there are no duties or taxes.
Ingredients
Aqua, Glycereth-26, Glycerin, Dimethicone, Polyglyceryl-3 Stearate, Cetearyl Olivate, Caprylic/Capric Triglyceride, Niacinamide, Methylpropanediol, Polysorbate 60, Butylene Glycol, Stearic Acid, Cetyl Alcohol, Carbomer, Arginine, Chlorphenesin, 1,2-Hexanediol, Allantoin, Stearyl Alcohol, Ethylhexylglycerin, Sodium DNA, Disodium EDTA, Adenosine, Pentylene Glycol, Myristyl Alcohol, Sodium Hyaluronate, Madecassoside, Lauryl Alcohol, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid.
PDRN Ampoule
3 months · Subscribe & save
4.9 from 4,200+ reviews
What people noticed first.
As seen in
ALLURE
VOGUE
COSMOPOLITAN
The results
Clinical results, at home.
An independent 12-week study, graded by dermatologists, with no injectables. These are the numbers, and the faces behind them.
Unretouched participant photos. Individual results vary. For cosmetic use only. Not intended to diagnose, treat, cure or prevent any disease.
92%
reported smoother, brighter-looking skin after one use
86%
said skin looked smoother, plumper and more radiant with consistent use
35%
increase in collagen production during clinical testing
Trusted by Beauty Insiders
They don't just
recommend it. They use it.
Why it works
Where creams stop, this keeps going.
Salmon DNA is close enough to our own that skin recognizes it and responds the way it knows how, by repairing itself.
1
It rebuilds, not coats
PDRN signals fibroblasts to produce collagen and elastin. It rebuilds structure instead of just coating the surface.
2
Clinic strength, at home
50,000 PPM is the highest topical PDRN available, and the same active used in in-clinic salmon-DNA facials.
3
A glow that compounds
It isn't a one-night glow. With daily use, results build the longer you stay with it.
What's inside
Four actives. Nothing for show.
A highly concentrated formula. Every ingredient earns its place: nothing for marketing, nothing for filler.
SALMON DNA · 50,000 PPM
Skin rejuvenator
Stimulates collagen, promotes cell regeneration and softens fine lines, for firmer, brighter skin.
HYALURONIC ACID COMPLEX
Hydration
Several molecular weights hydrate at different depths and lock moisture in.
NIACINAMIDE
Brightener and barrier
Improves clarity and texture, and supports a stronger, more even-looking barrier.
MADECASSOSIDE
Soother
A purified active from Centella asiatica that soothes and supports the skin's own protective barrier.
FULL INGREDIENT LIST
Aqua, Glycereth-26, Glycerin, Dimethicone, Polyglyceryl-3 Stearate, Cetearyl Olivate, Caprylic/Capric Triglyceride, Niacinamide, Methylpropanediol, Polysorbate 60, Butylene Glycol, Stearic Acid, Cetyl Alcohol, Carbomer, Arginine, Chlorphenesin, 1,2-Hexanediol, Allantoin, Stearyl Alcohol, Ethylhexylglycerin, Sodium DNA, Disodium EDTA, Adenosine, Pentylene Glycol, Myristyl Alcohol, Sodium Hyaluronate, Madecassoside, Lauryl Alcohol, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid.
The ritual
Morning or night, in under a minute.
STEP 01
Uncap
Start on clean, towel-dried skin.
STEP 02
Unlock
Unlock the pen and release 1–2 drops per area.
STEP 03
Apply
Press gently into face and neck.
STEP 04
Layer
Let it sink in, then moisturizer, SPF or makeup.
What to expect
Week by week.
WEEKS 1–2
Glow and hydration
These are the first things most people notice.
WEEKS 4
Texture
Skin renews in roughly four-week cycles. Around now it starts to feel denser and smoother.
WEEK 8+
Firmness and fine lines
This is the compounding part, and why the 3-month dose is the one most people choose.
The difference
Better skin. Less spend.
YURSLF
THE OLD WAY
✓
Rebuilds skin at the cellular level
✕
Only hydrates the surface
✓
Real salmon PDRN at 50,000 PPM
✕
Plant substitutes at 5,000–10,000 PPM
✓
One gentle daily step, sensitive-safe
✕
A stack of serums and clinic visits
$58/mo
$500+/mo
One daily ampoule in place of the serums, essences and in-clinic aesthetics.
Watch · 2 min
1 in 3 Women Treat Their Skin Wrong
Watch Felicia, Medical Esthetician explain the dos and dont's of skincare.
Questions
Everything you
might be wondering.
What exactly is PDRN?
PDRN (polydeoxyribonucleotide) is a regenerative ingredient used in clinics to stimulate skin repair. It signals your own cells to renew, which builds collagen, speeds turnover and improves hydration.
Is it really salmon DNA? Will it smell?
Yes, it is real salmon-derived PDRN rather than a synthetic or plant substitute. It is purified and odorless, so there is no scent at all.
How soon will I see results?
Most people notice glow and hydration within the first two weeks and texture around week four. Firmness and fine lines build over 8+ weeks.
How is this different from Rejuran?
Rejuran is an injectable used in clinics. This is a topical form of salmon DNA, processed into low-molecular-weight fragments so it can absorb through the skin with daily use at home.
Can I use it with retinol or tretinoin?
Yes. It is often layered with them to help support repair and barrier recovery. Patch-test first when you combine it with strong actives.
Is it pregnancy-safe?
Salmon DNA is a topical ingredient that does not enter the bloodstream, and it is considered suitable for use during pregnancy.
Will it replace Botox or fillers?
No. It improves skin quality, texture and fine lines. Injectables address muscle movement and volume, which is a different job.
Why subscribe?
Results build with consistent daily use. The 3-month subscription is 50% off with free shipping, and you can pause, skip or cancel anytime.
30-day promise
Glowing skin, or
your money back.
Give the ritual a full 30 days. If your skin doesn't look firmer, brighter and more hydrated, we'll refund you, and you don't have to ship anything back.
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